Services

CTC isolation & Enrichment

CTC Enumeration

What is CTC Enumeration?

CTC enumeration is an analytical service designed to derive quantitative results by isolating and purifying only live CTCs from the blood using
our proprietary HDM chip technology.

Advantages of CTC Enumeration

  • First Confirms the specific cancer type and enables tracking by verifying the presence of CTC markers for particular malignancies.
  • Second Enables the counting of cells expressing specific CTC markers.

Cytogen performs analysis of CTC marker expression using the Cellyzer CZ-1000, an advanced system integrated with our proprietary immunofluorescence (IF) staining analysis software.

The Cellyzer CZ-1000 eliminates the inherent subjectivity and lack of objectivity of traditional IF analysis by automatically generating results based on precise, pre-configured settings. By leveraging this automated platform, we deliver data services characterized by superior accuracy, speed, and reliability.

Furthermore, these results facilitate the tracking of treatment effectiveness through longitudinal monitoring of CTC count variations post-treatment. Beyond our core offerings, we provide a robust academic foundation by offering customized analysis services for specific biomarkers, tailored to the unique cancer types and research needs of our clients.

CTC Liquid Biopsy Analysis List

Cancer type Markers Target Application
Lung cancer EpCAM+, EGFR+, CD45- Monitoring CTC counts and EGFR expression levels.
Breast cancer EpCAM+, HER2+, CD45- Monitoring CTC counts and HER2 expression levels.
Prostate cancer EpCAM+, ARv7+, PSMA+, CD45- Monitoring CTC counts and ARv7 expression levels.
Pancreatic cancer EpCAM+, CD133+, CD45- Monitoring CTC counts and CD133 expression levels.
Optional CEP8 Identification of genetic mutations

* Analysis of these specific markers enables precision medicine tailored for individual patients.